In Las Vegas, Nevada, its reputation for providing instant success for those willing to try their luck draws in the hopeful and the naive. This constant influx of visitors also provides ripe targets for criminals of all varieties, confident they will never be caught. Unfortunately for them, most are proven wrong by the Las Vegas Police Department's night shift Crime Scene Investigation unit led by Gil Grissom. With almost obsessive dedication towards his quest for the facts, he and his elite team of investigators work various perplexing cases using scientific skills and equipment that are capable of finding valuable clues from the most seemingly unlikely sources. In a city of empty dreams and false fronts, Gil Grissom leads the quest for the one thing that can cut through the lies to the truth and ultimately justice, the evidence.